Royal Air Force Typhoon jets have joined forces with French aircraft in a joint strike on an underground arms cache in Syria operated by the IS group, as stated by the UK's MoD.
The location, located using reconnaissance, was believed to be housing weapons and explosive materials, the release indicated, and was positioned in mountainous terrain just north of the historic site of Palmyra in the heart of Syria.
"Our fighter planes used precision-guided Paveway IV munitions to strike a series of entry passages down to the site... preliminary assessments suggest the strike was effective," the MoD said.
There was no evidence of any harm to civilians in the operation on Saturday evening and every plane involved returned to base without incident, the MoD added.
The British jets were backed up by a Voyager tanker plane.
Daesh - also known as ISIS - enforced extremist governance over parts of Iraq and Syria until 2019.
"This strike demonstrates British leadership, and determination to operate in unison with our partners, to eliminate any resurgence of the terrorist group and their dangerous and violent ideologies in the area," UK Defence Secretary John Healey remarked.
British military aircraft have performed patrols over Syria to "deter any efforts to regroup" of IS subsequent to its defeat at the battle of Baghuz in 2019, the MoD reported.
"I extend gratitude to all the members of British forces who took part in this mission for their skill and their valour," Healey commented. "They were part of a great many British personnel stationed over Christmas and New Year. This operation, to take out terrorist threats who threaten our safety, shows how British military are always on standby, continuously, ensuring Britain's security domestically and influential overseas."
During December, the American forces executed what it called a "large-scale strike" against IS targets in the country, following an assault killed two US troops and a civilian interpreter in Palmyra.
The UN reports IS still has between 5,000 and 7,000 militants in Iraq and Syria.
